Abstract: Camel liver is a a traditional Sudanese treat that occasionally is associated with toxicity when consumed raw. This study is intended to throw light on the possible mechanisms and factors pertaining to such a toxicity. About 18 cats, Felis domestica, free from disease were divided into 6 groups; 5 groups being fed different treatments of camel liver while the control group was fed ox meat. Variations likely to occur due to seasonal differences were probed. Significant blood biochemical changes as well as tissue changes, suggestive of hepatorenal toxicity were observed in the groups fed camel liver of the rainy season and camel liver treated with ox bile. Results open up a vista for further investigation.