Abstract: Four groups of adult male Sprague dawley rats each consist of six animals. All animals were experimentally wounded in the dorsal neck area. Wounds of Group I rats each was treated with blank Vaseline-jelly (control), whereas wounds of Group II and Group III animals were treated with 5 and 10% Vaseline (Plantago major aqueous leaf extract in Vaseline), respectively. Wounds of Group IV rats each was treated with commercial solcoseryl-jelly as reference. The effects of vehicles on the rate of wound healing were assessed. Wounds treated with 5 and 10% Vaseline and solcoseryl�jelly significantly healed earlier and much faster as compared to wounds of control. These results strongly document the beneficial effects of plant extract for the acceleration of wound healing process.