Abstract: Gastrointestinal (GI) bleeding occurs from the mouth, esophagus, stomach, small intestines, large intestines to the anus. Variceal bleeding is a normal and severe side-effect of portal hypertension. It was a prospective analytical study conducted among 110 cases of acute gastrointestinal bleeding cases admitted in department of general surgery in a tertiary healthcare institute during December, 2013 to June, 2015. The 55 patients for banding and 55 patients who has undergone previous sclerotherapy were selected in the present study. Majority of the population were males in both the groups A and B (67.27 and 61.81%) whereas there were 32.72 and 38.18% females in group A and B, respectively with Mean age 49.58±15.6 years. In the present study, we observed that in group A, 83.63% of the cases became free from bleeding. In group B, the number was relatively lesser (63.63%). The prevalence of re-bleeding was found to be more among cases enrolled in group B (34.54%). Endoscopic banding procedure was found to be better as compared to sclerotherapy for management of gastrointestinal varices.