Abstract: There is a rare of information regarding the influence of age on cerebrospinal fluid (CSF) and blood components of the one-humped camels. To demonstrate these relationships, CSF and blood were collected from two age groups of male camels (1- >3 and 3-5 years). Most of CSF tested parameters (urea, creatinine, uric acid, total protein, non albumin protein) in large age group were showed a significant difference relative to small age camel group except glucose, albumin and electrolytes contents (Na, K and Cl). Age had no significant effect on the serum component except on the urea, creatinine and uric acid in the both age groups. These differences especially in CSF parameters between the two age groups may suggest that blood-brain barrier is not at the same stage of maturation or selective permeability.