Abstract: The activities of Glutamate Oxalo-acetate Transminase (GOT) and Alkaline Phosphatase (ALP) and the concentrations of cholesterol total protein, albumin and bilirubin were determined in the sera of healthy rural camels (Camelus dromedarius) in Butana area in Sudan in the summer (June, 7). The levels estimated were in general agreement with the normal levels reported by other investigators. The same investigations were carried in the sera of rural healthy camels in the rainy season (October, 15) in Butana, significant changes were observed in the estimates of albumin SGOT and ALP.