Abstract: This study was carried out to determine the effect of dietary supplementation of combiotics (probiotic+prebiotic, Makroton®) on body weight gain, feed consumption, feed conversion rate, carcass quality and serum biochemical parameters. A total of 264 daily Japanese quail chicks (Coturnix coturnix japonica) were used in this experiment. They were divided into 1 control and 3 treatment group each containing 66 chicks. Each group was divided into 3 subgroups each containing 22 chicks. The experimental period lasted 35 days. Control group was fed with unsupplemented basal diets. 0.5, 1.0 and 1.5 g kg-1 combiotic was added to diets of treatment groups 1, 2 and 3, respectively. At the end of the experiment, the effect of combiotic supplementation to diet on the BWG, FC, carcass yield of and serum biochemical parameters of quail were not statistically significant among the groups (p>0.05). FCR rate was determined as 3.19, 3.15, 3.14 and 2.87, respectively.