Abstract: A study was conducted with 48 Hanwoo calves from birth to 90 days to know the effect of natural feed additives on growth, feed intake and blood profiles. The calves were arranged in four groups; control, antibiotic (Neomycine 110 ppm), propolis (0.05%) and illite (2%) having 12 calves (male female ratio 6:6) in each. The claves were supplied pellet feeds ad libitum. They were allowed to suck mother’s milk and timothy grass hay were supplied after 1 month and multi nutrient block. Water was supplied ad libitum through the water tub. The significantly highest (p<0.05) BW and ADG were found in antibiotic fed calves than other groups. There were almost similar values observed in control and illite fed calves. Significant lowest (p<0.05) weight was observed in propolis fed calves. Highest feed intake was recorded in control group followed by antibiotic, illite and propolis group. Illite group seems to be suitable among the feed additives groups but the daily weight gain was statistically lowest (p<0.05). Blood profiles didn’t show any effects after addition of additives except significant reduction of A/G ratio. So considering all the factors both the natural resources, lllite and Propolis didn’t show potential for production of Hanwoo calf at pre-weaning.