Abstract: The present research evaluated the effects on spermatogenesis of feeding male goats with cottonseed cake. It was used thirty adult male goats, which were separated into two groups: one fed with 0.5 kg/animal/day of cottonseed cake and other fed with 0.5 kg/animal/day of corn, for 120 days. At the end of the experimental period, blood samples were collected for determination of serum levels of total proteins, glucose, cholesterol, urea, creatinine and triglycerides. Samples of semen were collected for laboratorial determination of quality, including density and spermatic pathologies. The obtained results revealed that administration of cottonseed cake to goats did not affect the quality of produced semen.