Abstract: The cross sectional study was conducted from October 2007 to April 2008 to determine seroprevalence and associated risk factors for seropositivity of FMD. Antibodies against non-structural protein of FMD virus (using 3ABC ELISA) were measured as indicator of exposure to the virus. An overall seroprevalence of 5.6% (48.4% at herd level) for FMD was found. Differences in geographical locations, age groups and herd sizes were risk factors found statistically (p<0.05) associated with the occurrence of FMD. Any successful and cost effective intervention project to control FMD should therefore, consider these risk factors during project formulation.