Abstract: During September to November, 2007, an outbreak of neonatal calf diarrhea occurred in Friesian calves on 8 dairy farms at Sulaibiya area, Kuwait. From each farm, fecal and blood samples were collected randomly from diarrheic calves aged 1-3 weeks and sent to the veterinary laboratories, public authority of agriculture affairs and fish resources to be tested for the evidence of cryptosporidium, rotavirus, coronavirus and Bovine Viral Diarrhea (BVD) infection. Cryptosporidium oocysts were detected in 38.8% (31/80) of the fecal samples, rotavirus in 28.8% (19/66) and BVD virus antibodies 62% (49/79) in serum samples. Coronavirus was not detected in 66 fecal samples tested. Cryptosporidium was detected on the 8 farms tested and found concurrently with rotavirus on 6 farms. On one farm, cryptosporidium was the only detectable cause of diarrhea.