Abstract: The aim of this study was to examine erythrocyte Superoxide Dismutase (SOD), Catalase (CAT) and Malondialdehit (MDA) level in bovine with hypodermosis. Study included 9 cattle diagnosed as hypodermosis (study group) and 10 healthy cattle (control group) making a total of 19 in the age group between 16 and 18 months montafon heifer. Parasitological examination in all larvae revealed Hypoderma bovis. No significant differences were observed in erythrocyte SOD, CAT activities and MDA levels between control and study groups. However, mean average of decreased SOD and CAT activities and increased MDA level associated with presence of oxidative stress and antioxidative imbalance in bovine with hypodermosis.