Abstract: This study was carried out to determine the prevalence and type of renal lesions in cattle and sheep that were slaughtered at Tiaret abattoir. A total number of 750 clinically normal cattle and sheep of different sex, age and breed were randomly selected and renal samples were taken for histopathological study. Out of 300 cattle and 450 sheep studied, 79 (17.55%) and 55 (22.66%), respectively had renal lesions including interstitial nephritis, glomerolonephritis, Acute Tubular Necrosis (ATN), epithelionephritis, cysts and amyloidosis. Interstitial nephritis was the most common observed lesion (7.77%) in sheep and 6.33% in cattle, respectively. The prevalence of renal lesions in animals aged >2 year was 17% in cattle (p = 0.18) and 32% in sheep (p<0.05). It is concluded that age is more important influence factor on renal lesions in sheep.