Abstract: Orthogonal Frequency Division Multiplexing (OFDM) is one of the main techniques proposed to be employed in fourth generation wireless systems. However, there are several hurdles that need to be overcomed before OFDM finds widespread use in modern wireless communication systems. The spectra of OFDM are not strictly band limited. As a result, the linear distortion such as multipath causes each subchannel to spread energy into the adjacent channels and consequently cause intersymbol interference (ISI). Moreover, the time variations of the channel destroy the orthogonality among the subcarriers and causes intercarrier interference (ICI). In this study, time domain Partial Response Coding (PRC) is proposed for eliminating interference without the need of cyclic prefix. The expression for the interference power with PRC is derived. Simulation results show that PRC in OFDM systems reduce the ICI power without decreasing the bandwidth efficiency.