Abstract: A simple model of the bubble column reactor to interpret the mass transfer phenomena has been proposed in this study and its numerical simulation has been done. The important non-adjustable parameters have been explained and their dependence on various adjustable parameters has been studied to understand the bubble column operation. Mass transfer model inside BCR has been proposed in this study and its numerical simulation has been done using MATLAB software to predict the two phase mass transfer behavior in BCR. Effect of change in operating condition, column geometry and physiochemical properties of the two phases has been studied in this study. This study may helpful to further understanding of two-phase flow in bubble column and its design.