Abstract: This study reports the physical-chemical characterization of polyacrylamide-co-methylcellulose and applications in concrete. Three ratio of polymers were used for the synthesis of copolymers: 95:5 (MC-PAAm), 85:15 (MC-PAAm) and 75:25 (MC-PAAm). In this process, acrylamide was considered more stable than methylcellulose. The materials obtained were analysed by TG, FT-IR and Scanning Electron Microscopy (SEM) techniques. In the nutshell, the results can be used to improve most of the characteristics of concrete. As the dosage of water-soluble copolymer increased, the demand of water gets decreased. The combined water content, absorption and compressive strength of the hardened cement pastes were increased by changing different ratio of polymers.