Abstract: Cloud computing are a new archetype move and many researchers are attempting to find out the factors affecting the cloud computing adoption in hospitals. This research aims to provide insights into the factors and the barriers that are expected to influence the adoption of cloud computing in hospitals. The primary data were collected by in-depth interviews with IT departments of different hospitals in India. The collected data was tested using multiple regression analysis. The Technology Organization and Environment (TOE) framework was considered for this study. The findings indicated that all the factors has a significant positive impact on the intention of hospitals to adopt cloud computing. The findings are expected to assist managers to evaluate possible adoption and increase their awareness about issues that influence the cloud adoption when planning to adopt it.