Abstract: This study aim to investigate the heavy metals residues in soil and vegetables from agriculture area in Wangkanai District, Kanchanaburi Province. The concentration of Zn, Cd and Cu found in soil of all vegetable gardens were higher than the standard of contaminated heavy metals in Thailand soil but lower than the standard of contaminated heavy metals in European soil. The determination of heavy metal residues in Chinese Kale, Celery and coriander showed that Cu and Zn were below the notification of the Ministry of Public Health No. 98 and World Health Organization (WHO). The safety level of pesticide residues in vegetables showed that only 10% of Chinese Kale and Celery found organophosphate and carbamate residues were in unacceptable level.