Abstract: A change in the curriculum and the learning objectives has brought complex challenge for teacher in explaining material and e-Books to learn. Teachers are faced with the challenge to find the right e-Books and learning material for their students. This study aims to propose a method of learning simplification to the instructional media to support learning in subjects that are considered difficult and has many various e-Books. This study is conducted to determine the suitable model of e-Learning design as academic learning material. It tested and evaluated the relationship between the design and material suitability. It used quantitative approach with research and development analysis for orientating website development. Furthermore, the data were analyzed using OLS (Ordinary Least Squares) method with e-Views Version 4.1. This study tested web display, quality of instructional media, expediency, classroom interaction and knowledge adsorption. The results showed a significant relationship among the tested variables and have significant result toward increased knowledge adsorption.