Abstract: Transmitter generally requires a power amplifier at its output stage. Application suchas telemetry of biological signals involves low power with low supply voltage into it. Low power circuits used in this transmission application requires larger loads to match with the output with high DC feed inductance when compared to high power amplifiers. Traditional power amplifier design for low power application uses various classes of amplifiers to avoid the output filters that degrade the efficiency. Class-E amplifier is anonlinear switching type power amplifier which produces high efficiency with the lowpower consumption. A new design methodology of Class-E power amplifier is proposedin this project which operates to the narrowb and range of 2.4-2.45 GHz and broadband range of 6.78 MHz-2.45 GHz is proposed. In the narrowband design inductance constraint is removed by varying the supply voltage. The broadband model is accomplished by high power and low power transistor. The efficiency of the power amplifier is increased by increasing the order of the input and output matching network. The circuits are simulated using Advanced Design Systems (ADS-2011).