Abstract: In this study, we solved the forced Korteweg-de Vries-Burgers (FKdVB) with variable coefficient arises in nonlinear wave propagation in an elastic tube with a symmetrical stenosis filled with varible viscocity fluid by two numerical methods, namely method of lines and finite-difference method. We then compared both numerical solutions with its progressive wave solution. Both methods solve the FKdVB equation with maximum absolute errors of 10-7.