Abstract: Due to increased levels of unrest and potential terrorist attacks, more studies on structures and their resistance to explosion are so imperative. Many existing structures cannot resist blast effects, therefore, improvement to their resistance to the explosive loading is required. The present study is an attempt to study the behavior of RC frames which having different levels of ductility (designed according to ABA code), these frames had been exposed to explosive loading. Taking into account the significant role of Fiber-Reinforced Plastic (FRP) in improving ductility, a comparison has been made between the behavior of high ductile frames and that of FRP. Analyses were carried out by using Abaqus/Explicit Software. It should be noted that the proposed models were verified through laboratory testing.