Abstract: This study examines the effect of FDI, human capital on economic growth in SSA. Using a panel of 24 countries in SSA, over the period 1970-2006, the study estimated a fixed effect model, on different levels of human capital that are capable of interacting with FDI to increase growth. The major finding of the study is that there exists weak effect of FDI and different measures of human capital on economic growth in SSA.