Abstract: This research purposes were to develop the administration management model on infectious waste of Tambon health promoting hospital to comparing their knowledge and behavior after training. The sample composed of 31 officers as a agent who is in the Tambon health promoting hospital Phetchabun Province’s population which have been selected by a purposive sampling technique. The research design was just one group pre-test and post-test. The data collection was analyzed by percentage usage and t-test. The study results are as following: The Administration Management Model (ADD MODEL) development on infectious waste management was rated as a high efficiency. The officers of Tambon health promoting hospital had knowledge and behavior on infectious waste management after training was rated higher that before training (p<0.05).