Abstract: This study discusses the status of agricultural biotechnology of some developing countries including Nigeria. Agricultural biotechnology has the potential to solve local agricultural needs andto greatly increase food production.Some advances in agricultural biotechnology with emphasis on crop production are treated. The issue of genetically modified organisms and crops, together with their associated concerns have also been discussed.Various factors promoting and inhibiting the application of agricultural biotechnology in developing countries, with particular reference to Nigeria are enumerated and discussed. Solutions to the identified problems have been proffered, which would make agricultural biotechnology worthwhile in Nigeria.