Abstract: The effectiveness of Cashew Nut Shell Liquid (CNSL) extracted by soxhlet extraction process was evaluated against termites (soldiers and workers castes) in the laboratory. The experimental design was a Completely Randomized Design (CRD) with 8 treatments, which was replicated 4 times. The mortality rates of the various treatments differed significantly (p< 0.05) from the control treatment at each exposure time period. However, there was no significant different (p>0.05) between the mortality of the standard termiticide and the CNSL at 6, 8 and 10% treatment levels, as they all gave a 100% kill of termites at the 90th min for the soldiers caste and 60th min for the workers caste. Zero persent mortality was recorded in the control cages throughout the exposure period. There is therefore an indication that CNSL can be used to control termites.