Abstract: The aim of our study was to develop specific methods that make possible to identify and visualize focuses of ecosystem pollution for the determinationof the permissible anthropogenic impact boundaries and prediction of their development. The two-level spatial zoning method is considered through the example of an environmentally unfavorable region of the Russian Federation. The set of analytic methods is proposed, which was applied to determine the preliminary boundaries of areas using the clustering procedure, while the algorithms of correlation and regression analyzes allow to assess the uniformityof specific environmental characteristics in selected areas.