Abstract: Karoon river as biggest Iran’s river has always subjected to lateral changes due to its specific conditions such as big floodwaters and its soil texture. In this research it is tried to calculate erosion rate of meanders of Karoon river within South of Ahvaz to Darkhovein using results of Mike 11 model and also application of an analytical model. Annual erosion rate of Karoon river at its meanders was calculated by incorporating of results of mathematical model, geotechnics, river geometrical attributes (river’s width and curve radius of arcs), Einstein-Brown bed load equation and analytical model. In order to assess accuracy of calculations river’s shore displacement has been obtained using existing maps which its comparison with calculated results shows that mathematical model, analytical model, bed load equation and other considered parameters for calculation of erosion rate were reasonable and appropriate and simple analytical model of erosion rate could provide relatively proper values of river’s shore erosion rate at studied range.