Abstract: Eczema Disease (ED) is the most common form of skin inflammation in humans. Most of the skin disease is curable at initial stages with the advancement of technology. So, an early detection of skin disease can save the patient’s life and prevent the progression of the disease. It is proposed to have a study on the diagnosis of ED using BPNN (Back Propagation Neural Network) in cloud computing approach due to that BpNN is currently widespread research area in medicine and plays an important role in a decision support system. In this study, an attempt has been made to make use of BpNN in the medical field along cloud computing to detect ED.