Abstract: The nature of geological and hydrological conditions in Northern Region is complex resulting in low drilling success rate and high variability of borehole yields. The voltaian formation in the Northern Region is known to have high-low potential of groundwater resources as the flows mainly occur in fracture zones with some areas characterised by low porosity and along bedding planes for some areas. This kind of formation occurs in the Northern belt of the region and a smaller portion in the South. The groundwater resource potential within Northern Region was studied using typical hydrogeological factors such as transmissivity, overburden thickness, borehole success rate and groundwater potentiometric level. The research targeted areas of high groundwater success rate so as to minimise the gap in the computation that would be affected as a result of dry boreholes. The study considered 38 boreholes out of functional boreholes numbering 890 within Northern Region. The permanent groundwater reserve and the recoverable groundwater reserve were estimated to be approximately 533,108,995.2×mn;106 m3 and 213,243,598.1×mn;106 m3, respectively for the aquifer basement complex of 38 boreholes.