Abstract: Hypertensive Diseases in Pregnancy (HDP) are one of the leading causes of maternal and fetal mortality and morbidity. The cause of preeclampsia-eclampsia remains unknown and risk factors for the development of preeclampsia are less well defined. We conducted a case-control study on pregnant women presenting to Tabriz Al-Zahra and Taleghani hospitals from August 2003 to August, 2004. Patients were studied in 2 groups of cases (64) and controls (64). Maternal age and BMI in case group was significantly higher than control group. The difference of education, gravidity, smoking and history of abortion between case and control groups was not significant. Preeclampsia history and inadequate prenatal care in case group were significantly high. The difference of previous SGA newborn, birth interval and same paternity between case and control groups was not significant. Preeclampsia risk factors in multigravida women include: High maternal age and BMI, history of preeclampsia, positive past medical history and inadequate prenatal care.