Abstract: Polymer suspensions with narrow particle size distribution and a diameter of 0.2-0.4 um was synthesized by two different routes, suitable for use in Biotechnology: emulsion polymerization in conditions of surfactant synthesis at the interface and without surfactant in the presence of the polymer which is incompatible with formed polystyrene and participating in the formation of structural and mechanical barrier in the interfacial adsorption layer of particles.