Abstract: This study interpersonal problems, psychological flexibility and quality of life in people with symptoms of social anxiety disorder and normal. This is causal-comparative study. The population was all female high school students with purposive sampling of which 40 students with symptoms of social anxiety disorder and 40 normal students that demographic variables such as age, education, socioeconomic status and gender were similar in the two groups. To collect the data, the scale of Interpersonal Problems (IIP-60), Acceptance and Action Questionnaire (AAQ-II) and the Social Anxiety Scale Adolescents (SASA) was used for data analysis variance of the two groups were examined. The results indicate that the two groups of students with symptoms of social anxiety on Interpersonal problems and its subscales except controlling and psychological flexibility there were no significant differences.