Abstract: This study presents data on change of the electrophysiological function of retina as a reaction to the decrease of interalveolar space in patients with major dental diseases of various origin. Our electroretinographic study has revealed an improvement in the amplitudes of b-wave of maximum (total) ERG and b-wave of rod (scotopic) system of retina electrogenesis, a positive component reflecting the macula functioning (P50) and the improvement of the retinal ganglion cells functioning (3rd neuron of optic pathway) the amplitude of the negative component (N95) in patients upon restoration of the occlusal vertical dimension.