Abstract: The study presents the ovarian reserve criteria in 93 girls with secondary amenorrhea. The ovarian reserve was evaluated by the hormone level: FSH, LH, E2, AMH, Inhibin B and ultrasonic markers ovarian volume and the number of antral follicles in the section. In 9.7% of cases the low ovarian reserve was detected. The factors that resulted in reduction in the ovarian reserve were specified and the predictive indices were estimated.