Abstract: In twenty-five Nubian goats the effect of CymelarsanR and Oxytetracycline was studied. Twenty goats were infected with T. evansi. Serum glutamic oxaloacitic transaminase(GOT), glutamic pyruvic transaminase (GPT) and alkaline phosphatase (ALP) levels were increased post-infection. In CymelarsanR and in the combination treated groups the normal level was reached in less time. They were restored to normal in the CymelarsanR and in the combination treated groups.