Abstract: Administration of progesterone in form of intravaginal devices in she camel has produced a uniform plasma concentration of progesterone depending on the dose of the device. Subcutaneous implant and intramuscular injection of progesterone produced a non-uniform plasma concentration of the hormone, possibly because of the damage to injection site in the muscle as reflected in elevated plasma creatine kinase activity. This suggested that the intravaginal device administration maybe a better route to provide a constant concentrations of progesterone in camel.