Abstract: Maternal mortality remains one of the most daunting public health problems in developing countries and reduction in maternal mortality have been identified as a prominent component of the United Nations Millennium Development Goals. A five year (2001-2005) review of all recorded maternal deaths was carried out in the leading government hospitals in Ondo State-Nigeria. A total of 556 deaths occurred out of 11,568 deliveries (MMR480/100,000). Obstructed labour, severe anemia, abortions and native drug intoxication were the leading causes of death. Pregnancies at too young and old ages, lack of formal education and being unbooked were also significant risk factors. Employment status of mothers was also identified as associated factor of maternal mortality. Mass formal education, public enlightens to encourage utilization of antenatal facilities, prompt referrals of complicated cases and adequate equipping of the hospitals is suggested.