Abstract: A study is devoted to results of the analysis of the main spheres of criminal activity made by a transnational organized crime on materials of the Kyrgyz Republic, the Russian Federation and the Republic of Kazakhstan at the present stage. There are formulated and stated the current tendencies and specific circumstances, influencing on commission in the specified states of such most dangerous crimes as: the international terrorism, crimes in the sphere of drug business, kidnapping and trafficking of people, crimes in the sphere of economy, illegal international weapons trafficking.