Abstract: This study was conducted to estimate the prevalence of the parasitic diseases in different animal species in Kassala area, eastern Sudan during 2004 up to 2006. A total of 1396 samples which were referred to Kassala Veterinary Research Lab were retrospectively studied. The samples were collected from different animal species; 1185 bovine, 139 ovine, 19 caprine, 46 equine and 7 camels. The study detected the following parasitic diseases: Anaplasmosis, theileriosis, trichostrogyliasis, microflariasis, coccidiosis, trypansomaiasis, moniezia sp. and mange.