Abstract: The aim of this study is to measure the impact and effects of entrepreneurship orientation, market orientation on improving business overall performance on Jordanian small and medium enterprises, through entering deeply in the innovation and entrepreneurship fields. This study used a research questionnaire in order to make an analysis process for the research variables. The main study objective is to investigate the relationship of adopting the orientation of entrepreneurship and market inside business organization, analysing the main effects for entrepreneurial and market orientation factors on the development of the overall business performance through measuring the effects on the innovation orientation performance. The study represented by (autonomy, competitive advantages and risk taking) and market orientation presented by (customer orientation, competitor orientation and inter-functional orientation). The way that this study chose the independent variables lied on their capabilities on improving the organization state between competitors based on competitive conditions. The study data and information had been gathered by regression sample model and analysed using Statistical Package for the Social Sciences (SPSS).