Authors : Robert Bodkowski, Piotr Kuropka, Bozena Patkowska-Sokola, Katarzyna Czyz, Ewa Sokola-Wysoczanska, Wiesalwa Walisiewicz-Niedbalska, Zygmunt Usydus and Hanna Gwardiak
Abstract: Based on elaborated or modified procedures, fish oil was enriched in EPA+DHA fatty acids which content increased from 32.4-83.3% (preparation EFO) while milk fat was enriched in t11C18:1 (VA) and c9, t11C18:2 (CLA isomer) fatty acids from 1.8 and 1.3-16.5 and 12.3%, respectively (preparation EMF). Linoleic acid c9, c12C18:2 contained in grapeseed oil was applied for synthesis of its conjugated dienes of c9, t11 and t10, c12C18:2 configuration in amount of 76.5% (preparation MGO). The composition of Lpid Complex (LC) was elaborated based on these preparations and it contained 28.7% CLA+VA and 27.8% EPA+DHA. An application of lipid preparations in in vivo study on the rats considerably limited unprofitable changes within coronary vessels and cardiac muscle induced by the diet rich in saturated fatty acids. Elaborated preparations inhibited a decrease in vascular bed size from 5.7-24.7%, an increase in both cardiac ventricles thickness from 17.3-50.6% and myocytes size from 3.6-34.8%. The lowest decrease in vascular bed size was noted in the groups supplemented with EFO and LC. The thickness of both ventricles increased to the lower degree in groups EMF and LC while the size of myocytes in groups EFO and LC.
Robert Bodkowski, Piotr Kuropka, Bozena Patkowska-Sokola, Katarzyna Czyz, Ewa Sokola-Wysoczanska, Wiesalwa Walisiewicz-Niedbalska, Zygmunt Usydus and Hanna Gwardiak, 2014. The Influence of Bioactive Lipid Preparations on Cardiac Muscle and Coronary Vessels State in Rats. Journal of Animal and Veterinary Advances, 13: 223-230.