Abstract: In the current era, information has become the main driver for the success of business organizations. Management information systems are concerned with providing sufficient and timely information to managers in order to take appropriate decisions and improve performance in business organizations. Small businesses are increasingly becoming an essential part of a nation's economies; this means that the success of small businesses has a significant impact on the economy. The adoption of management information systems in small businesses can generate significant competitive advantages for small businesses which will positively impact the economy. The business environment is dynamic and involves risks and uncertainty about the future. These risks and uncertainties lead to many important, critical and complex decisions to survive in the market, especially small businesses. Since small businesses need to gain market share, improve profitability and achieve long-term success, they cannot do without relying on MIS to make decisions. This study aims to review the organizational, technological and human factors associated with the use of management information systems in business organizations. This study also serves to contribute to a better understanding of the influence of management information systems on the decision-making process in small businesses. The results of the study showed that management information systems have a positive effect in identifying the problem, the speed of problem discovery, the analysis of decision-making steps, the speed of decision-making and the quality of decision-making in small businesses.