Authors : Moein Faramarzi, Saeed Kiaalvandi, Farnaz Iranshahi and Mohammad Lashkarbolooki
Abstract: Lctoferrin (LF) is an iron-binding glycoprotein plays an important role in the non-specific immune system in fish and mammals. Common carp (Cyprinus carpio) was fed bovine LF supplemented diets (0, 200, 400 and 600 mg kg-1 diet) for 4 weeks. The effect of dietary LF on immune function and resistance to Aeromonas hydrophilla challenge was determined. The level of LF in diet had a significant force on survival following A. hydrophilla challenge with fish fed the 600 mg kg-1 LF diet having significantly superior survival than control fish. There was increase in activity of non-specific and specific immune parameters (lymphocytes count, macrophage oxidative burst, serum lysozyme and bactericidal activities against A. hydrophilla) with addition of LF to diets. While there was not a corresponding increase in activity of total leukocytic count and neutrophil adhesion test. The increased resistance to A. hydrophilla with increasing dietary concentration of LF seemed to correspond with an enhancement of non-specific immune functions. In conclusion, dietary LF supplementation could be enhances the non-specific immunity and diseases resistance in common carp (Cyprinus carpio).
Moein Faramarzi, Saeed Kiaalvandi, Farnaz Iranshahi and Mohammad Lashkarbolooki, 2011. Assessment of Dietary Bovine Lactoferrin in Enhancement of Immune Function and Disease Resistance in Common Carp (Cyprinus carpio). Journal of Fisheries International, 6: 41-45.