Abstract: Zinc status has been shown to influence various cell-mediated immunologic mechanisms. These cell-mediated mechanisms are important in preventing mucocutaneous infections caused by Candida albicans. This study evaluated the relationship between zinc status and recurrent vulvovaginal candidiasis by comparing plasma zinc in 51 patients with recurrent vulvovaginal candidiasis and 50 control healthy age-matched women. The results indicated that zinc concentration in plasma in patients with recurrent vulvovaginal candidiasis and control group showed no significant difference between case and control group (p = 0.605), 4(8%) women of control group and 5(11/1%) women of patients group had zinc concentration lower than normal. Also, no significant difference between the mean plasma zinc concentration (case group 48-189 µg dL 1 and control group 57-120 µg dL 1) in the patient and control group (87 µg dL 1, std 23.5, 74.9 µg dL 1, std 13 µg dL 1) (p = 0.031) .
M. Zangeneh , S.D. Siadat , M. Jamshidi , M. Alijani , B. Farhoudi and M. Valizadeh , 2008. Zinc Level of Serum in Recurrent Vulvovaginal Candidiasis. Research Journal of Biological Sciences, 3: 515-518.