Abstract: Apricot (Prunus armeniaca) is a stone fruit consumed fresh or dried. Turkey is the top world producer with the Malatya area supplying over half of the crop. Market demands are stringent as apricot trees need to be resistant to both heat and cold while producing fruits satisfying the customer. Therefore, crop improvement involves many parameters. The genomes of peach (Prunus persica) and Japanese apricot (Prunus mume) have been sequenced. Both belong to the same family as apricots. Consequently, around 250 genes were collected for both species along with the reference Arabidopsis. Both targeted and non targeted approaches were applied to diversify the range of protein functions covered. Thus, a set of genes involved in amino acid metabolism was studied along with a second group selected based on the phenotype conferred. Comparison of the three plants shows that gene allocation to a given function is conserved assignment of a clear gene to gene correspondence between organisms is a delicate task and clear gene counterparts do not necessarily share the same cellular compartment.