Authors : J.A. Badmus , A.L. Adedeji , E.O. Omotoso , A.O. Oyewopo and A.O. Akintola
Abstract: High intake of dietary fat has been implicated in the incidence of cardiovascular disease. The effects of 3 Nigerian dietary oils (crude palm oil, refined palm olein of Malaysian origin and crude groundnut oil) were assessed on plasma lipid profile of wistar albino rats. Twenty rats were randomly divided into four groups of 5 per group. Rats in the control group were given normal feeds only while in addition the treated groups were given 1 mL of additional crude palm oil, groundnut oil and refined palm olein oils as supplement adlibitum for 28 days. Results showed decline in High density lipoprotein (HDL-C), Low density lipoprotein cholesterol (LDL-C) and Total Cholesterol (TC) concentrations in all the treated groups compared to control group. HDL-C reduction was significant only in groundnut oil treated group (p< 0.05) while LDL-C percentage concentration reduction were 14.6, 44.9 and 10.8% and TC decreased by 18.18, 25.59 and 17.14% in groups treated with palm oil, refined palm olein and groundnut oil, respectively. Plasma triacylglycerol (TG) was signicantly higher only in the group treated with refined palm olein (p< 0.05) while other treated groups showed insignificant reduction. There was no significant difference in plasma lipid ratios of LDL-C/HDL-C and TC/HDL-C in the treated groups compared to control group whereas there was higher Triacylglycerol/ HDL-C ratio as shown only in the group treated with refined palm olein. The present findings showed that refined palm olein oil like palm oil and groundnut oil has no adverse effect on plasma total cholesterol and LDL-C except in plasma triacylglycerol and TG/HDL-C ratio.
J.A. Badmus , A.L. Adedeji , E.O. Omotoso , A.O. Oyewopo and A.O. Akintola , 2008. Effects of Three Nigerian Stable Oils on the Plasma Lipid Profile of Wistar Rats. Research Journal of Medical Sciences, 2: 193-196.