Abstract: Despite the wealth information that have been gathered about Mycobacterium tuberculosis over many decades of research and the availability of live attenuated vaccine, tuberculosis remains to be an expanding global health crisis. Understanding Tuberculosis (TB) epidemiology among certain population is essential for the management of overall TB health program. Thus, the present study was carried out to describe the epidemiology of TB among migrant workers in Qassim region, Saudi Arabia. The 165 migrant patients from the neighboring countries majority from South East Asia accessing the TB services at Regional TB center at Qassim were included in this study. The majority of subjects 72 (43.6%) were from Indonesia and India 38 (23%) followed by Nepal 12 (7.2%). Out of 165 patients, 95 (57.6%) were female compared to 70 (42.4%) males with housemaid being the highest (44.8%) with regard to occupational category. Majority of the cases were of middle age and low socio economic status. Fever, loss of appetite, loss of weight and cough were the chief clinical presentations. Among the total cases, 9 cases (5.4%) were suffering from Diabetes. Over all, Prevalence of TB among migrant is relatively high. Preventive measures for early diagnosis should be performed especially in migrant worker from high-prevalence countries.