Abstract: Cystic Hydatidosis (CE) is a Zoonosis and caused by larva stages of Echinococcus granulosus (metasestoda) in intermediate host, eggs of echinococcus released through the faeces from infected dogs and eggs ingesting infects humans. Cystic echinococcosis is one of the most important geographically widespread helminth zoonosis, more often in countries those nourishment sheeps especially in rural areas. A study was undertaken to determine the extent of spread of human cystic echinococcosis among moghan plain nomads in Ardabil Province and to evaluate the effectiveness of health education in increasing community knowledge regarding the disease. Households were interviewed using a questionnaire to evaluate their knowledge of hydatid disease (cystic echinococcosis). Three different types of educational activity were undertaken in the community and the increase in knowledge at 6 and 12 months post-education was compared to baseline levels. Prevalence of infection increased significantly with age. So far no survey was conducted to determine analysis risk factors for the human hydatidosis in Ardabil province, so, using ELISA test and for the first HCF-Ag then Ag-5 and Ag-B and questionnaires forms, the prevalence of this disease was detected in moghan area in this province. Hospital records defiend that cystic echinococcosis is frequent in Moghan Area of Ardabil province. The present study designed to determined the ser-opositive rate and to analysis risk factors of disease for people living in this region. In this survey 2680 serum samples were randomaly collected from the normal population the everywhere of six shingles of Moghan plain. Sera was storaged in -70°C in Ardaebil medicine. In first stage of test for screening the sera was tested using enzyme linked immunosorbent-assay protocol and HCF-Ag. Afterwards the serology results all the sera were examined using ELISA test and specific antigens such as Ag-B and Ag-5 for cystic echinococcosis and Em2⁺ for alveolar echinococcosis. The serology results were analyzed by Logistic regression using SPSS 18. Of 2680 serum samples 162 sera (6.9%) and (0.4%), respectively for CE and AE were positive. Women were more than men (21 vs. 11.2%) for CE. The age group of 4-19 showed the lowest rate and the 20-39 and 40-59 showed the highest rate of infection. The rate of prevalence in this province shows somehow a resemblance with the other cities in Iran. Considering the lifestyle in this province a complementary study is suggested in all related cities.