Authors : Ashraf Elkomy, Soad Belih, Mohamed Aboubakr and Mohamed Morad
Abstract: The effect of amoxicillin on some biochemical changes in broiler chickens was investigated in 30 apparently healthy broiler chickens. The chickens were divided into 3 groups and treatment was orally administered in drinking water for 5 consecutive days. Group 1; Untreated control, group 2; Treated with amoxicillin (10 mg kg–1 b.wt.) and group 3; Treated with amoxicillin (20 mg kg–1 b.wt.). Blood samples were taken at the end of experiment, serum samples were used for biochemical analysis of AST, ALT, total protein, albumin, creatinine and uric acid. Amoxicillin in both doses produce an elevation in AST, ALT, creatinine and uric acid and non-significant elevation in total protein and albumin. In conclusion, administration of amoxicillin in both doses (10 and 20 mg kg–1 b.wt.) produces some biochemical changes and these changes was transient. Care must be taken when used amoxacillin therapeutically in poultry farms because of their adverse effects on liver and kidney functions.
Ashraf Elkomy, Soad Belih, Mohamed Aboubakr and Mohamed Morad, 2019. Biochemical Changes Following Water Medication of Amoxicillin in Broiler Chickens. Research Journal of Pharmacology, 13: 42-46.