Authors : G. Godazandeh , A. Khalilian , I. Maleki , H. Fakheri , F. Mahboob , H. Khani and S. Afzali
Abstract: Stomach is widely used for esophageal reconstruction in esophageal cancer surgery. The aim of this clinical trial was to study the effects of pyloromyotomy in patients with esophagectomy and gastric transposition for esophageal cancer surgery, in terms of gastric emptying and postoperative complications. In this randomized controlled trial on patients with esophageal cancer admitted for esophagectomy and gastric transposition in two medical centers of Sari, Iran, Gastric radioisotope scanning with labeled radiosolids was performed on patients 6 to 8 weeks after operation to evaluate transposed gastric emptying with or without pyloromyotomy. All the patients were followed up for 6 months postoperatively being assessed clinically. The mean age of the subjects was 46.6�7.2 years and 12 were female pathologic reports of 23 patients were Squamous Cell Carcinoma (SCC)and remaining 7 were adenocarcinoma. In patients with pyloromyotomy, 11 cases had delayed gastric emptying time and 4 patients were normal. In patients without pyloromyotomy, 9 patients had delayed gastric emptying time and 6 were normal. There was no statistical significance in gastric emptying rate and postoperative complications between the two groups. Based on the results it is recommended that esophageal resection and gastric transposition be performed without any additional intervention to improve gastric drainage.
G. Godazandeh , A. Khalilian , I. Maleki , H. Fakheri , F. Mahboob , H. Khani and S. Afzali , 2008. Randomized Clinical Trial of the Effects of Pyloromyotomy on Transposed Gastric Emptying Rate in Patients with Esophageal Cancer, after Esophagectomy and Cervical Esophagogastrostomy . Surgery Journal, 3: 6-12.